Yes—if the blood comes from a licensed blood bank or hospital that follows testing and matching guidelines. Safety does not depend on whether you personally know the donor, but on:

·       Proper screening for infections (HIV, hepatitis B and C, syphilis, etc.).

·       Correct blood group matching and cross‑matching.

·       Careful storage and handling of blood components.

Modern transfusion practice is designed to make serious reactions rare. Receiving untested blood outside medical facilities (for example at home or in informal clinics) is unsafe and should be avoided.