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Transfusion in Older Adults – Special Considerations

Older adults (senior citizens) often have unique health challenges. When they need transfusions, doctors must balance benefits and risks carefully.

Why older adults may need transfusions

Common reasons include:

·       Chronic anemia due to long‑term illnesses (kidney disease, bone marrow disorders, nutritional deficiencies).

·       Cancer and chemotherapy.

·       Gastrointestinal bleeding (from ulcers, polyps, or other conditions).

·       Major surgery (hip replacements, heart bypass, etc.).

Transfusions in older adults can:

·       Improve energy and ability to do daily activities.

·       Reduce breathlessness and chest discomfort.

·       Support recovery after surgery or illness.

Special risks and careful dosing

Older adults are more likely to have:

·       Heart disease or reduced heart function.

·       Kidney problems.

·       Higher sensitivity to fluid overload (too much volume too fast).

Because of this:

·       Doctors often use smaller, slower transfusions, sometimes one unit at a time, and then re‑assess.

·       They monitor closely for signs of fluid overload: breathlessness, swelling, rising blood pressure, lung congestion.

·       Diuretics (water tablets) may be given with transfusions in some patients to help prevent overload.

Individualized decisions

In older adults, doctors think about:

·       Overall frailty and functional status (can they walk, live independently?).

·       Other illnesses and life expectancy.

·       The patient’s own values and preferences (for example, whether they prioritize comfort, independence, or aggressive treatment).

Sometimes, the goal may be:

·       To relieve symptoms (like fatigue and shortness of breath) and improve quality of life, even if the underlying disease cannot be cured.

Families should feel free to ask:

·       What the aim of transfusion is (cure, prolong life, symptom relief).

·       How many transfusions are likely to be needed.

·       How the team will watch for side effects.

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